Browsing by Author "Bagcivan, I"
Now showing items 1-20 of 20
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Comparative relaxant effects of YC-1 and DETA/NO on spontaneous contractions and the levels of cGMP of isolated pregnant rat myometrium
Demirkoprulu, N; Cetin, M; Bagcivan, I; Kaya, T; Soydan, AS; Karadas, B; Cetin, A (ELSEVIER SCIENCE BV, 2005)This study was designed to compare the effects of YCA (3-(5-hydroxymethyl-2'-furyl)-1-benzyl indazole), a nitric oxide (NO)independent soluble guanylate cyclase activator, and diethylenetriamine-NONOate (DETA/NO), a NO ... -
Comparison of effects of cyclooxygenase inhibitors on myometrial contraction and constriction of ductus arteriosus in rats
Karadas, B; Kaya, T; Bagcivan, I; Kaloglu, C; Guvenal, T; Cetin, A; Soydan, AS (ELSEVIER SCIENCE BV, 2004)The aim of this study was to compare the tocolytic effect of a selective cylooxygenase-2 inhibitor, DFU (5,5-dimethyl-3(3-fluorophenyl)4-(4-methylsulphonyl)phenyl-2(5H)-furanone), indomethacin and nimesulide on myometrial ... -
Comparison of effects of formoterol and BRL 37344 on isolated term-pregnant rat myometrial strips in vitro
Yurtcu, N; Cetin, A; Karadas, B; Imir, AG; Kaya, T; Erselcan, T; Bagcivan, I; Cetin, M (ELSEVIER SCIENCE BV, 2006)This study was designed to compare the effects of beta-adrenoccptoy agonists formoterol and BRL 37344 on spontaneous contractions and the levels of cAMP and cGMP of myometrial strips isolated from timed-pregnant rats. ... -
Effect of chronic renal failure on the purinergic responses of corpus cavernosal smooth muscle in rabbits
Kilicarslan, H; Yildirim, S; Bagcivan, I; Ayan, S; Sarac, B; Sarioglu, Y (WILEY, 2002)Objective To examine purinergic relaxation responses in chronic renal failure (CRF) in an experimental rabbit model, and thus evaluate the possible involvement of the purinergic system in erectile dysfunction with CRF. ... -
Effect of hypothyroidism on the nitrergic relaxant responses of corpus cavernosal smooth muscle in rabbits
Sarac, B; Yildirim, MK; Bagcivan, I; Kaya, K; Kilicarslan, H; Yildirim, S (WILEY, 2006)Background: The incidence of hormonal dysfunction as a cause of impotence remains controversial. However, several recent studies have reported evidence of hormonal abnormalities in 25-35% of impotent men. Hypothyroidism ... -
Effect of L-NAME on decreased ileal muscle contractility induced by peritonitis in rats
Koyluoglu, G; Kaya, T; Bagcivan, I; Yildiz, T (W B SAUNDERS CO, 2002)Background/Purpose: It is now well established that intestinal inflammation is associated with disturbed contractility. The aim of this study was to determine the effects of peritonitis on longitudinal ileum smooth muscle ... -
Effect of peritonitis on gallbladder smooth muscle contractility in guinea pigs
Kaya, TT; Koyluoglu, G; Karadas, B; Yildiz, T; Bagcivan, I; Ceran, C; Gokgoz, S (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004)Background. The mechanisms involved in the impaired gallbladder contractile response in peritonitis are unknown. The aim of this study was to determine the effect of peritonitis on the contraction and relaxation responses ... -
Enhancement of EFS-induced contractions, by agmatine, in guinea pig gallbladder smooth muscle strips
Yildirim, S; Aydin, C; Koyuncu, A; Bagcivan, I; Sarac, B; Sarioglu, Y (SPRINGER TOKYO, 2005)Background. Electrical field stimulation of gallbladder muscle strips produces frequency-dependent contractions by activating cholinergic nerves. The cholinergic motor function of the gallbladder and enteric system is also ... -
Hydrogen-potassium ATPase inhibitors induce relaxation on rabbit prostatic strips in vitro
Bagcivan, I; Gokce, G; Ayan, S; Yildirim, S; Sarac, B; Kilicarslan, H; Sarioglu, Y (WILEY, 2002)Background: To determine the relaxant effect of omeprazole and lansaprazole, hydrogen-potassium (H+ -K+ ) ATPase inhibitors, on rabbit prostatic tissue in vitro . Methods: Male New Zealand white rabbits were sacrificed and ... -
In vitro effects of intravenous anesthetics on the sphincter of Oddi strips of sheep
Background: Intravenous anesthetics are often used for conscious sedation in endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincter of Oddi (SO) manometry. This study was designed to investigate the ... -
In vitro motility changes in Roux limb after Roux-en-Y reconstruction
Dogan, N.; Gokakin, A. K.; Koyuncu, A.; Bagcivan, I; Aydin, C.; Topcu, O.; Yildirim, S. (COMENIUS UNIV, 2014)Background: The aim of this study is to compare the motility of Roux limb with that of normal segment. Materials and methods: Rats were divided into 3 equal groups as control, Roux-en-Y (Group A) and Roux-en-Y with vagotomy ... -
Interactive effect of sevoflurane with isradipine or inclomethacin on spontaneous contractile activity of isolated pregnant rat myometrium
Gursoy, S; Kaya, T; Kunt, N; Karadas, B; Bagcivan, I; Kafali, H (ELSEVIER SCI LTD, 2004)Volatile anesthetics, calcium antagonists and non-steroidal anti-inflammatory drugs inhibit contractile activity of myometrial smooth muscle. The aim of this study was to investigate the interactive effect of sevoflurane ... -
Investigation of the mechanism of nicotine induced relaxation in rabbit corpus cavernosum in vitro
Bagcivan, I; Gokce, G; Yildirim, S; Sarioglu, Y (SPRINGER, 2004)In order to determine whether nicotine acts on corporal smooth muscle, the mechanism of its effect on strips of rabbit corpus cavernosum was studied in vitro. Rabbit corpus cavernosum muscle strips were mounted in an organ ... -
Investigation of the mechanism of nicotine-induced relaxation on the sheep sphincter of Oddi
Bagcivan, I; Kaya, T; Turan, M; Goktas, S; Demirel, Y; Gursoy, S (CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2004)Possible mechanisms for nicotine-induced relaxation were investigated in the isolated sheep's sphincter of Oddi. Sheep's sphincter of Oddi rings were mounted in tissue bath with modified Krebs-Henseleit solution and aerated ... -
Relaxation effects of adrenomedullin in carbachol-precontracted rabbit internal anal sphincter
Koyuncu, A; Yildirim, S; Aydin, C; Bagcivan, I; Sarac, B (SPRINGER-VERLAG TOKYO, 2003)Background The internal anal sphincter is a specialized continuation of the circular smooth muscle layer of the rectum. It has been found that internal anal sphincter tonus is significantly increased in the majority of ... -
Relaxation effects of adrenomedullin in isolated rabbit corpus cavernosum smooth muscle
Gokce, G; Bagcivan, I; Kilicarslan, H; Yildirim, S; Gultekin, YE; Sarioglu, Y (BLACKWELL PUBLISHING LTD, 2004)To clarify the pharmacological effects of adrenomedullin, a potent vasodilator and hypotensive peptide isolated from human phaeochromocytoma cells, on corpus cavernosal smooth muscle in vitro, as the intracavernosal injection ... -
Relaxation induced by omeprazole does not change in diabetic rabbit corpus cavernosum
Ayan, S; Sarioglu, Y; Yildirim, S; Gokce, G; Bagcivan, I (WILEY, 2001)Objective To investigate the changes in relaxation responses to omeprazole in corpus cavernosal strips from rabbits with diabetes induced by alloxan. Materials and methods Diabetes was induced in 10 New Zealand white ... -
The role of K+ channels on the inhibitor effect of sevoflurane in pregnant rat myometrium
Kafali, H; Kaya, T; Gursoy, S; Bagcivan, I; Karadas, B; Sarioglu, Y (LIPPINCOTT WILLIAMS & WILKINS, 2002)Volatile anesthetics and K+ channel openers inhibit spontaneous contractions in myometrial smooth muscle. Volatile anesthetics modulate K+ channel activity We investigated the role of two K+ channel blockers on the effect ... -
Soluble guanylyl cyclase activators increase the expression of tolerance to morphine analgesic effect
Durmus, N.; Bagcivan, I; Ozdemir, E.; Altun, A.; Gursoy, S. (COMENIUS UNIV, 2014)Objectives: It is aimed to investigate the effects of guanylyl cyclase activation and inhibition on acute morphine antinociception and the development of tolerance to its effect. Background: Nitric oxide-soluble guanylyl ... -
Vasorelaxant effect of opioid analgesics on the isolated human radial artery
Gursoy, S; Bagcivan, I; Yildirim, MK; Berkan, O; Kaya, T (CAMBRIDGE UNIV PRESS, 2006)Background and objective: Arterial grafts are prone to vasospasm. Opiold analgesics are commonly used in the perioperative course of cardiac surgical procedures. Therefore, we investigated the direct effects of morphine, ...